Bone remodeling is supported by thyroid hormones.

Calcitriol may also be involved in the activation of RANKL synthesis.

Growth factors are involved among those factors that influence osteogenesis locally.

Increased blood calcium levels from external sources are the result of calcitriol action.

Non-collagenous proteins represent only about 10% of the organic bone component.

The predominant type of collagen in bone is type III.

Osteocytes are involved in the regulation of mineralization.

Sialophosphoproteins may also be involved in hydroxyapatite binding.

Phosphatases play an important role in bone remodeling. Alkaline phosphatase is associated with matrix vesicle, while acidic with osteoclasts.

Osteonectin inhibits mineralization.