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Metabolism of bones; mineralization. (GM)

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Sialophosphoproteins include osteocalcin.

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During the mineralization of an organic matrix (eg enamel), the growing crystals require more space and therefore the extracellular matrix is partially degraded by enzymes.

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The basic multicellular unit manages to rebuild its bone segment to an average of four months.

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The presence of osteocalcin in urine is considered a positive marker of induced bone formation.

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All bone and tooth cells are the product of mesenchymal stem cells.

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Bone sialoprotein (BSP) initiates the mineralization process.

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Osteocytes are connected to each other by a tight junction.

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Carbonate dehydratase catalyses the formation of H2CO3 in the osteoclast with the consequent formation of H+ and HCO3-. Both ions then pass through the channels into the resorption zone.

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The enzymes produced by osteoclasts include cathepsins.

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Cadherins are also proteins that interact with calcium.

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