1. ester, 2. anhydride, 3. acyl halide, 4. amine

1. carboxylic acid 2. anhydride, 3. acyl halide, 4. amine

1. carboxylic acid, 2. amide, 3. acyl halide, 4. ester

1. anhydride, 2. amide, 3. carboxylic acid, 4. ester

diastereomers

constitutional (structural) isomers

unrelated

enantiomers

the same compound

A is a amide functional group; B is an ester functional group; C is an acid group; D is a ketone

A is a amide functional group; B is an alcohol; C is an ester functional group; D is a ketone

A is a amide functional group; B is an alcohol; C is an acid group; D is an aldehyde

A is an ester functional group; B is an ether; C is an amide functional group; D is an aldehyde

diastereomers

constitutional (structural) isomers

unrelated

enantiomers

the same compound

The order from best leaving group to worst leaving group is b, a, d, c.

The order from best leaving group to worst leaving group is c, d, a, b.

The order from best leaving group to worst leaving group is b, d, c, a.

The order from best leaving group to worst leaving group is d, b, a, c.

8

4

1

16

2

CH₃C(O)O^- is a bad leaving group as it is a strong base with a weak conjugate acid.

CH₃C(O)O^- is a good leaving group as it is a strong base with a strong-medium conjugate acid.

CH₃C(O)O^- is a good leaving group as it is a weak base with a strong-medium conjugate acid.

CH₃C(O)O^- is a bad leaving group as it is a weak base with a strong-medium conjugate acid.

diastereomers

constitutional (structural) isomers

unrelated

enantiomers

the same compound