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Phase 3 Medicine 2026

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A 20 year-old patient presents with an overdose of paracetamol.

What are the important factors that need to be considered in order to make a proper risk assessment for the paracetamol poisoning? (more than one answer is correct)

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A 70 kg 45-year-old man presents 4 hours following an ingestion of 20x5mg oxycodone. In your ED, he is drowsy but rousable, HR 70 bpm, BP 110/70, RR 6/min, O2 sat 90% RA, GCS 8 (E1V2M5).

What is the most appropriate treatment for this patient?

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A 60kg 19-year-old

university student presents after a weekend of partying and taking

methamphetamine with friends. She complains of feeling anxious with palpitation

and chest pain. In your ED, she looks slightly agitated. Her RR at rest is 24/min, HR

110 bpm, BP 140/90mmHg and her SaO2 is 95% at rest, temp 37°C. ECG shows sinus tachycardia.

What would be the most appropriate management for this patient?

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For the same patient above, the paracetamol level at 4h is 200 mg/L. What is the next most appropriate step?

Paracetamol Treatment Nomogram (Rumack-Matthew Nomogram)

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A 45

kg 17-year-old girl presents 1.5 hours following ingestion of 30 x 500 mg of

paracetamol which she washed down with 5 glasses of wine. She appears

well and is cooperative.

Should this patient receive decontamination for her paracetamol poisoning? Please choose the most appropriate answer.
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For the same patient, what investigations are needed for the assessment of her paracetamol poisoning?

Choose all the appropriate investigations (more than one answer).

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A 16-year-old girl with a history of ADHD is brought to ED by her parents. She is

agitated, restless and complains of palpitation. HR 140 bpm, BP 180/100 mm Hg,

pupils 7 mm. She is hyper-reflexic and looks very anxious. ECG shows sinus tachycardia.

When questioned, she says she has been taking more lisdexamphetamine to help her to perform well in her examinations.

Question:

Which of the following is the most appropriate

medication to treat this patient?

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Which of the following drugs bind with activated charcoal? Please select all that apply.

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Please match the drug with its antidote:

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Most ingestions in children are accidental. Which of the following medications has a high risk of toxicity in children?
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