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BCH2011 - Structure and function of cellular biomolecules - S1 2025

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Here's an image from that same protein, zooming in on a beta turn and with four amino acids highlighted in ball and stick representation. I've drawn around one amino acid.

Image failed to load

With respect to the beta turn, which statement describes the circled amino acid?

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Your lab partner has stumbled upon a really important sequence of mRNA (sadly, they won't tell you why it's important, but... whatever).

In an act that frustrates you more than people listening to music on PTV without headphones, they have also forgotten the conventions of writing out nucleotide sequences.

The note they left stuck to your laptop was written as follows:

3'-UAAGGCGUAUAGC-5'

To appease the biochemistry Gods, write out the corresponding sequence of coding strand DNA (properly, in 5' to 3' orientation) that encodes this mRNA.

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The image below shows a cartoon representation of the structure of part of a protein.

Because this isn't an exam question, I have crudely labelled these (1 to 4) with my best free-hand mouse skills.

Image failed to load

Assign the correct label to each number.

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Consider the following strand of mRNA:

5'-AUUAGCCUCG-3'

Write out the sequence of coding strand DNA (written 5' to 3') that encodes this mRNA. 

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OK, a little trickier this time. Take your time and think about what the question is asking and the information it is providing you with.

Consider the following region of a non-coding strand of a DNA duplex:

5'-TGCTACATCT-3'

Write out the sequence (in 5' to 3' orientation) that would be produced following transcription of DNA to mRNA from this region.

Be careful not to type any spaces or additional characters. For example, if you think the answer is 5'-AGCC-3', simply type AGCC.

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Consider the following region of a coding strand of a DNA duplex:

5'-CCTTCCGAGC-3'

Write out the sequence of the corresponding mRNA (in 5' to 3' orientation) that would be transcribed from this region. 

Be careful not to type any spaces or additional characters. For example, if you think the answer is 5'-AGCC-3', simply type AGCC.

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Shown below is part of the coding strand for a gene.

5'-GGGCGAAGGCGGGCTCGGCCGGAAGGGGTGGGGTCGCCGCGGCTCCCGGGCGCTTGCGCGCACTTCCTGC-3'

Which of the following primers would act as the reverse primer (i.e. it would anneal to the coding strand) for part of this sequence ?

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*NOT GOODBYBE THERE ARE MOAR QUESTIONS*

Shown below is part of the coding strand for a gene.

5'-GGGCGAAGGCGGGCTCGGCCGGAAGGGGTGGGGTCGCCGCGGCTCCCGGGCGCTTGCGCGCACTTCCTGC-3'

Which of the following primers would act as the forward primer (i.e. it would anneal to the non-coding strand) for part of this sequence ?

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The following sequence of RNA forms a “hairpin” structure. The duplex region contains all Watson-Crick base pairs without any gaps or mismatches.

5'-AAGCGAUAUGGCCAUUCCCAUAUCGCUAAC-3'

In the space below type the sequence of either of the two regions that form a duplex with each other. Be careful not to type any spaces or additional characters. (Do not enter in 5' or 3'. For example, if a potential answer was 5'-AAUUGG-3' then you would simply type: AAUUGG.)

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The following sequence of RNA forms a “hairpin” structure. The duplex region contains all Watson-Crick base pairs without any gaps or mismatches.

5'-UGGGAAAUGGCGGGAGACCGCCAUAAACGG-3'

In the space below type the sequence of either of the two regions that form a duplex with each other. Be careful not to type any spaces or additional characters. (Do not enter in 5' or 3'. For example, if a potential answer was 5'-AAUUGG-3' then you would simply type: AAUUGG.)

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