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Elective_2nd year_Step 1_med

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A patient, who has been on glucocorticoids for a long time, experiences

exacerbation of their illness, decreased BP (=blood pressure), and weakness

upon discontinuation of the medication. How can this be explained?

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A 70-year-old male

patient with chronic bronchitis has been given codeine to help relieve his

persistent cough. Which mechanism is used by codeine to exert its antitussive

(cough-suppressing) effect?

   

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A 20-year-old patient complains of general

weakness, dizziness (=vertigo), and quick fatigability. Blood test results show

Hb = 80 g/L. Microscopic

examination reveals abnormally shaped erythrocytes. What is the most likely

cause of this condition?

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A

patient shows a significant increase in aspartate aminotransferase (AST)

activity in the blood serum 12 hours after experiencing an acute episode of

retrosternal pain. This finding is characteristic of: 

 

 

 

 

 

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There was a

significant increase in MB isoform activity of creatine phosphokinase (CPK-MB)

and LDH-1 (lactate dehydrogenase 1). What is the most likely diagnosis? 

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A 3-year-old child with fever was given aspirin, which

led to increased erythrocyte hemolysis. The resulting hemolytic anemia may be

due to a congenital deficiency in the following enzyme:

 

   

   

 

 

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A 1.5-year-old child

presents with both cognitive and physical developmental delays, discoloration

of skin and hair, and a decrease in catecholamine concentration in the blood.

When a few drops of a 5% solution of trichloroacetic acid were added to the

child's urine, it turned olive green. These changes are indicative of the

following pathology of amino acid metabolism:

 

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A donor

skin transplantation was performed on a patient with extensive burns. On the 8

th

day, the graft looked swollen and changed its colour. By the end of the 11

th

day, graft rejection began. Which cells are involved in this process? 

 

 

 

 

 

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A patient complains of

frequent bowel evacuations, especially after consuming fattening foods, and

experiences body weight loss. Laboratory examination reveals steatorrhea and

hypocholic feces. What is the most likely cause of this condition? 

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Aspirin has its

anti-inflammatory effect due to inhibiting cyclooxygenase activity. Which

biologically active acids will decrease as a result of aspirin intake? 

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