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During intense exercise, as seen in the cricketer above, sweat is produced by sweat glands. Although sweat initially contains both water and electrolytes, some electrolytes are reabsorbed as sweat moves through the duct. Compared to blood plasma, the final sweat that reaches the skin surface is:
Name the technique you will use to create the concentrated solution of the molecule of interest you have identified.
Vaccines are designed to provide controlled and mild exposure to a probable infection and prepare our immune system to better defend us when the real infection hits us.
For COVID-19,
the spike protein was used in vaccines to generate an immune response. Let’s
assume that the spike protein has multiple epitopes as shown above. Which out
of the listed B cells will be able to identify the antigen to produce
corresponding antibodies which can fight against the COVID-19 infection?
Let us try to develop the vaccine design strategy for this spike-protein based vaccine? The goal will be to make high concentrations of this spike protein in the lab which can then be mixed with supporting chemicals to create the final vaccine formulation. What information do you need about the spike protein to start vaccine design?
Remember the trekking trip we took to Ladakh during the lectures and how we stepped onto a rusty nail? The image above shows the wound site. Identify the components of the immune system marked on the figure.
The pathological lab extracts the bacterial cells from a sputum sample provided by Amulya after 3 weeks of medication and cultured the bacteria in the lab. Given his prolonged and worsening symptoms, the technician should use -------- concentration of the antibiotic than regular in the antimicrobial susceptibility test.
The skin is a significant barrier that forms part of your innate immune system. Match the features in Column A with their function in Column B
Describe any one internal threat which the immune system is constantly keeping in check to keep you healthy.
Amulya was unfortunately diagnosed with tuberculosis (a baterial infection) and doctors prescribed the appropriate first line antibiotics. Even after 3 weeks of medication, Amulya’s symptoms kept on worsening. What could be a possible reason for this?
As life evolved further, some aspects of the immune system were preserved over time while some were lost. Can you propose a strategy to track this evolution of features of the immune system over time?