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DEV3011 - Experimental developmental biology and disease modelling - S1 2026

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Conditional deletion of a gene from E8.5 of the mouse embryo induces ectopic Wnt signaling in the anterior region. What sort of phenotype would this produce?
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A cell in the early mouse blastocyst is in contact with other cells on all sides. What is the most likely outcome?
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Which statement below is CORRECT?
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Consider the image below of an E6.5 mouse embryo.

What does X point to?
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What process sets up the dorsal-ventral axis in Xenopus embryos?
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What is the amphibian equivalent of Hensen’s node?
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What is the curved area of pale cytoplasm in many early amphibian embryos called?
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What is a genetic suppressor screen?
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How can the affected gene be identified in an ENU mutagenesis screen?
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A PhD student has conducted the ENU screen in mice and has observed a phenotype in the G1 as shown below.

d

 What is this an example of?
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