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DEV3011 - Experimental developmental biology and disease modelling - S1 2026

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You seek novel genes involved in apoptosis in C. elegans. What technique would you use?
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What is the function of the C. elegans ced-9 protein?
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What happens to FGFR's when FGF's bind?
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Isolated cells from the dorsal part of a frog embryo can form back cells if isolated and grown in culture and when transplanted into the belly region, they form back cells. This is an example of what developmental phenomenon?
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A researcher plans to use CRISPR/Cas9 for non-homologous end joining (NHEJ) in the mouse embryo. What is NOT part of the method?
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A student has used DAPI staining to observe a C. elegans specimen. What does DAPI stain?
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In cells of the dorsal neural tube, Smad2 has become phosphorylated. What does this mean?
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Which cell type below has the lowest degree of potency?
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A researcher wants to study the development of endothelial cells, and decides to make a transgenic zebrafish to visualise endothelial cells using time-lapse imaging as they develop.  What does the researcher need to make such a transgenic?
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What method could you use to detect where in the embryonic mouse neural tube the enzyme lactate dehydrogense is located?
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