DEV3011 - Experimental developmental biology and disease modelling - S1 2026

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Consider the image below of an E6.5 mouse embryo.

What does X point to?

In the inner cell mass

❌

Hensen’s node

❌

Anterior visceral endoderm

❌

The primitive streak

✅

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A PhD student has conducted the ENU screen in mice and has observed a phenotype in the G1 as shown below.

 What is this an example of?

A targeted mutagenesis screen

❌

A partially successful recessive genetic screen

❌

Mice unable to eat white chocolate

❌

A successful dominant screen

✅

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In the image below of the CRISPR/Cas9 system,  what does the black arrow denote?

Guide RNA

❌

A targeted gene sequence

❌

CRISPR protein

❌

Cas9 enzyme

✅

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The image below shows DAPI staining. What is is staining?

Cell cytoplasm.

❌

Cell walls.

❌

Only somatic cells.

❌

Cell nuclei.

✅

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Which is the ligand in the image below (A, B ,C or D)?

D

0%

A

0%

C

0%

B

❌

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How is the interaction among two population of cells below best described?

Juxtacrine

✅

WNT signaling

❌

Endocrine

❌

FGF signaling

❌

View this question

Consider the image below of an E6.5 mouse embryo.

What does X point to?

In the inner cell mass

❌

Hensen’s node

❌

Anterior visceral endoderm

❌

The primitive streak

✅

View this question

A PhD student has conducted the ENU screen in mice and has observed a phenotype in the G1 as shown below.

 What is this an example of?

A targeted mutagenesis screen

❌

A partially successful recessive genetic screen

❌

Mice unable to eat white chocolate

❌

A successful dominant screen

✅

View this question

Consider the image below of an E6.5 mouse embryo.

What does X point to?

In the inner cell mass

0%

Hensen’s node

0%

Anterior visceral endoderm

❌

The primitive streak

0%

View this question

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