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DEV3011 - Experimental developmental biology and disease modelling - S1 2026

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A DEV3011 student has conducted Alcian Blue staining and gets the result shown below.

What is specifically stained in the result above?

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A particular Hox gene is expressed in thoracic vertebra T1, and it does not exhibit functional redundancy. What is the likely effect of a homozygous null mutant for this Hox gene on the T1 vertebra?
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Tetrapod limbs are thought to have evolved from which structures?
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Complete the following sentence. Limb loss in snakes involves loss-of-function mutations in the ….
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A subset of Hox genes plays a key role in phase I patterning of which limb axis?
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A DEV3011 student has conducted Alcian Blue staining and gets the result shown below.

What is specifically stained in the result above?

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Different species of the Australian lizard genus Hemiergis

have different numbers of digits.

Developmentally, what is the most likely cause of this variation in digit number?

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A DEV3011 student has conducted Alcian Blue staining and gets the result shown below.

What is specifically stained in the result above?

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0%
100%
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View this question
A DEV3011 student has conducted Alcian Blue staining and gets the result shown below.

What is specifically stained in the result above?

0%
0%
0%
100%
View this question
You find that over-expression of the TOX3 transcription factor gene in the limb bud mesenchyme of mouse produces stunted limbs by E14.5. What method could you use to test if ectopic expression of the gene has the same or similar effect in the chicken embryo limb bud mesenchyme?
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