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Chemistry and Biochemistry

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Substances formed during the degradation of heme are called:

pigments

As the name suggests, these are colored

substances. Assign to each of them its colour:

Biliverdin

Bilirubin

Urobilinogen

Bilicyanin

Stercobilinogen

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Select which of the non-protein nitrogenous substances the following statement applies to:
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Of the substances present in the blood plasma, which contain nitrogen in their molecule, protein have by far the largest proportion (65-85 g/L). However, other (so-called non-protein) nitrogenous substances are also of diagnostic importance.

The largest share among non-protein nitrogenous substances in blood plasma consists of waste substances - end products of nitrogen degradation.

Assign its origin to the formula of the relevant waste substance:

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 Determine the

type of hyperbilirubinemia if the following values ​​have been obtained:

serum

urine

total

bilirubin

direct bilirubin

total bilirubin

direct bilirubin

14 μmol/L

3,5 μmol/L

-

-

 

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A combination of two enzymes is used to

determine serum urea.

Write them down in the order in which the

reaction proceeds.

1.     

2.     

Select

the reactant whose absorbance is measured in this determination:

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Evaluate the electropherogram of

blood serum proteins:

plazma

Evaluation of total

protein (CB):

level

Evaluation of individual fractions:

Albumin

level

α1

level

α2

level

β

level

γ

level

 

Serum protein electrophoretic pattern:

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Match the correct definition:
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Select the

principle on which the method for determining the following proteins is based.

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Identify the protein:

microprotein with a

molecular weight of

 around 12 kDa

, produced mainly by

myeloid and lymphoid cells, plasma concentration about 1-2 mg/L

tumour marker, rises

with a decrease in glomerular filtration

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Identify the protein:

glycoprotein produced by the liver, α2β2

tetramer, acute phase reactant, plasma concentration about 1 g/L

it binds very tightly to the hemoglobin

molecule, the resulting complex does not pass through the glomerulus, it is

quickly absorbed by RES cells

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